3 Most Dangerous Joint Pain Medications

dangerous joint pain medicationsIf you’ve seen a doctor for joint pain, there’s a very good chance (near 100%) that medication was offered as the solution. First, you may try acetaminophen (Tylenol) over the counter, which is often recommended for soreness.

If that doesn’t cut it, you may progress to non-steroidal anti-inflammatory drugs (NSAIDs), which are often used as a first-line treatment, even by joint pain “specialists.” If your pain is bad enough, you may even get a prescription for Celebrex, the newer (but not improved) NSAID on the market.

Unfortunately, these three common medications for joint pain are also among the most dangerous, and here’s why …

3. Acetaminophen (Tylenol)

Excess acetaminophen is a poison to your liver, and overdoses are a leading cause of acute liver failure in the United States. It’s not hard to overdose, either. Take a combination of products, multiple doses in a day, or combine the drugs with alcohol and you could be well on your way to fatal liver damage.

Acetaminophen may also cause potentially fatal skin reactions, known as Stevens-Johnson Syndrome (SJS), toxic epidermal necrolysis (TEN), and acute generalized exanthematous pustulosis (AGEP), often without warning.

2. NSAIDs (Aspirin, Ibuprofen, Aleve)

Aspirin, ibuprofen (Advil, Motrin), and naproxen sodium (Aleve) are examples of NSAIDs, which are notorious for increasing your risks of heart attack (Vioxx, anyone?). And all NSAIDs are hard on your gastrointestinal tract, leading to potentially fatal side effects such as bleeding in your digestive tract, ulcers and perforation of your stomach or intestines.

That’s bad enough … but NSAIDs also disrupt cartilage synthesis and actually speed up the destruction of cartilage and joints.[i] Yes, it’s a sad irony that one of the most common treatments for joint pain in the United States may actually cause your joints to break down more quickly.

1. Cox-2 Inhibitors (Celebrex)

Celebrex is also an NSAID, although it belongs to a “newer generation” known as cox-2 inhibitors. To get an idea of just how dangerous these drugs are, every other cox-2 inhibitor (including Vioxx and Bextra) has been removed from the market because of their unacceptably high risk of heart attack, stroke and other heart events.

Celebrex is not immune, however. Taking 400 mg of Celebrex twice a day for about 33 months may increase your heart attack risk by 340 percent. Researchers noted “an increase in risk by a factor of two or three” for myocardial infarction, stroke, congestive heart failure, or cardiovascular-related death among people taking Celebrex, compared to placebo.[ii]

Other common adverse reactions include abdominal pain, diarrhea, flatulence, peripheral edema, indigestion, accidental injury, dizziness, sinusitis, upper respiratory infection, rash and sore throat. Elevated liver enzymes can also occur, as can fatal gastrointestinal events and skin reactions.

Hello Super Joint Support®… Goodbye Pain

dangerous joint pain medicationsIt took us years to formulate Super Joint Support®, because in it we’ve included a proprietary blend of all-natural ingredients designed to nourish, support and possibly even regenerate your joints. It’s unlike any other, as it combines cartilage-building, joint-lubricating and pain-relieving properties into one maximum-strength formula for immediate relief.

Yet, unlike so many other products, the relief isn’t temporary … it relieves inflammation to deliver long-term pain relief too, and goes to work rebuilding and regenerating your aging cartilage, making it a permanent joint solution.

Super Joint Support® contains the synergistic joint nutrients chondroitin sulfate, hyaluronic acid, glucosamine sulfate potassium (a natural cox-2 inhibitor!), hydrolyzed collagen type II and more. Plus, it’s all packaged in a formula that contains 72 ionic trace minerals to ensure rapid absorption and assimilation into your body.

In all my 15 years of experience as a health and fitness expert, I can tell you this: I’ve never seen anything better than Super Joint Support® to help improve joint mobility and flexibility and rebuild worn out joint cartilage. That’s why I’ve made special arrangements for you to try it risk-free today. You can see how it compares below … if you have joint pain, trying Super Joint Support® is the easiest decision you’ll ever make.

dangerous joint pain medications


[i] Am J Med. 2009 Sep;122(9):836-42.

[ii] N Engl J Med 2006; 355:885-895


Filed Under: Arthritis, Medications, Super Joint Support
Written By:  Updated:
my avatar

Jesse Cannone, CFT, CPRS, MFT

Jesse is the co-founder and visionary CEO of The Healthy Back Institute®, the world-leading source of natural back pain solutions. His mission as a former back pain sufferer is to help others live pain free without surgery and pharmaceuticals.

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6 thoughts on “3 Most Dangerous Joint Pain Medications”

  1. George Folsey Jr. says:

    I’m 75 and have little or no cartilage left in both knees. I’ve tried a Synvisc
    injection in each knee and it has helped a little. I also do an Egoscue Menu of
    exercises which has helped more that anything. I take some supplements and
    I am in favor of them so I would like to try your Super Joint Support. Thank you
    for the opportunity.

    1. Steve says:

      George, Our our complete approach to joint pain and reduced cartilage, please read below…

      Heal n Soothe, is a Proteolytic Systemic Enzymes formula, designed for two primary purposes,
      To breakdown and remove excess metabolic waste including excess scar tissue, that can build up inside the Joints, Blood Vessels, Soft Tissues and in our Organs. Once the enzymes attach to that metabolic waste, it is then processed by the body and removed from the body.

      The second specific function of the enzymes is to regulate the biological processes that control the bodies inflammatory response, so if you can remove the metabolic waste from the body and then control the bodies inflammation, your body will then be better to be able to repair is self…


      Super Joint Support, is a specific blend of Type II Collagen, Glucosamine, Chondroitin and MSM, designed to help the body stimulate Chondrocytes, the very cells that can regenerate joint cartilage.

      Further 72, Water soluble Ionic trace minerals were added, for bone, joint and ligament support as well as support the body with a balanced approach to having the body be and function in a balanced state again allowing the body to heal its self.

      We added Vitamin K2, D3, and B12 , as co-factors to the Minerals and the Collagen to help them work even better, and finally we added a natural analgesic in the form of White Willow Bark to help the body deal with pain as well as ALA for nerve based pain.

      That said, they both are great products for helping to control Inflammation and to help heal soft tissue so for optimal results, we would suggest one of several options:
      1. Each product can be taken separately and at different times, meaning only taking one product for several months at a time, and not using the other product during those months, this way you can gauge the effect of each product separately .
      2. Heal n Soothe can be taken first for several months, to clean out and prepare the joint for recovery, before starting Super Joint Support, and after several months, both Heal n Soothe and Supper Joint Support can be taken daily till results are achieved.
      3. For optimal results, we suggest taking both Heal n Soothe and Super Joint Support, daily till results are achieved

      Note: Results do vary and there is no way to gauge a time line for use of these product, however, we have seen Heal n Soothe produce results in a matter of days and from clinical results it takes about 12 to 16 weeks for metabolic optimization to start to take place in the joint.

      Thanks for asking…



      1. Luella Biendarra says:

        1. Wife want’s to know if this is okay with an ileostomy?
        2. Wrong spelling of VERY in final note. VARY is the correct word here.

  2. Steve says:


    Based on what you have indicated about your wife’s condition, we know of no contra-indications but we have to suggest that she consult her physician as only they know her complete medical history and only they can answer that question with certainty…

    Thanks for Asking

    Steve HBI Staff

  3. Ann Batten says:

    My 2 bottles of Heal N’ Soothe should arrive next week, and am anxious to try it. I’m 80 and have been very active, health conscious & healthy until 4 years ago when arthritis set into my joints – knees, hip, neck & shoulders. I’ve had my R shoulder replaced last year & L hip surgery booked this May. I’m anxious to get off Tylenol & Meloxipam that I don’t feel is helping much. I’ve never taken pills until the last 3 years, & I want off!. After couple of months of H n’S I will order your Joint Support. I’m very excited to try these products and am totally on board with your way of thinking – – mine too!
    Thank you for trying to help!!!

  4. Steve HBI-Staff says:

    Ann, I love reading stories about individuals, taking responsibility for their health regardless of age or affliction…

    Great Job and keep up the winning attitude, it helps everyone!


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