Fibrin: The Sticky Protein Behind Joint Pain and Inflammation


Bonus Content: The 5 WORST Foods to Eat If You Have Joint Pain or Arthritis

The sticky clumps covering the red blood cells pictured above is called fibrin. It’s your body’s first response to injury and pain.

Fibrin itself is not bad, unless it gets out of control.

Fibrin dictates how healthy and flexible every part of your body stays as you age. Lingering pain, loss of flexibility, and chronic inflammation can all be traced back to out of control fibrin levels.

Not that you’ll hear much about fibrin from most pharmaceutical companies… They know once you understand what it is and how it works, you can reclaim a pain-free life. And stop wasting money on their dangerous pain pills.

WATCH: The 5 WORST Foods to Eat If You Have Joint Pain or Arthritis

Fibrin: just the facts

Fibrin is an insoluble protein that acts as a first responder whenever your body is injured.

When the call for help goes out, fibrin molecules rush to the scene.

Shaped like long threads, each fibrin molecule interlaces to form a thin mesh around your wound.

This mesh is critical for trapping the platelets and red blood cells needed to form blood clots.

Without fibrin, even small wounds would just keep bleeding. Fibrin mesh is the base material for clots, scabs, scars, and eventual healthy skin.

When everything is in perfect working order, the fibrin rushed to the injured site is returned to your body as you heal.

After a few days of repairs, your system sends in a second clean-up crew of enzymes to dissolve the excess fibrin and leave your muscles, nerves, and blood vessels just as they were before you were hurt.

Unfortunately, most of our bodies aren’t in perfect working order. When we hurt, we take pills, and pain pills cancel the body’s signal for enzymatic clean-up crews. Fibrin keeps rushing to the scene.

Over time, the fibrin molecules thicken and stiffen, forming scar tissue masses that can block blood vessels, interfere with muscle function, and lead to chronic inflammation.

Fibrin malfunction means major pain

This fibrin malfunction is no laughing matter. Excess scar tissue restricts blood flow and oxygen throughout your body, slowing down your healing process and keeping you in pain longer. As the scar tissue thickens, it reduces your range of motion and contributes to chronic pain.

A prime example of this process is fibromyalgia. The pain and suffering of fibromyalgia have been linked to an excess of fibrin in your muscle tissues.

Known as fibrosis, this condition can spread to affect every muscle and organ in your body.

Excess fibrin is associated with the aches and pains of getting older.

After all, the longer we live, the more we do to interfere with our natural healing systems — and studies show that our internal fibrin control systems begin to decline around age 27.

It doesn’t take long for fibrin overgrowth to become a real quality of life issue.

Reversing excess fibrin

Fortunately, it doesn’t take long to reverse fibrin overgrowth. The key is re-activating your body’s natural fibrin clean-up crew.

This crew is made of proteolytic enzymes, a group responsible for breaking down protein molecules.

They hit fibrin masses and literally eat them away. As an added bonus, proteolytic enzymes cleanse toxins from your blood, fight viruses, and fortify your immune system.

Unfortunately, your regular diet alone won’t overcome the massive drop in natural proteolytic enzyme production as you age.

Not only are most modern foods lousy nutritional sources, but the best naturally occurring proteolytic enzyme food sources are not a significant part of our normal diet.

You can get proteolytic enzymes from plant sources like pineapple stems, caper leaves, and papaya, but they need to be extracted in a lab. Unless you have one at home, you’ll want a proteolytic enzyme supplement.

It’s no surprise Big Pharma doesn’t want you to ask “what is fibrin” and discover the truth about how fibrin is keeping you in pain – and can be safely and easily eliminated.

If everyone understood the basic mechanics of the fibrin response and how pain pills mess things up, their sales would plummet.

They want you on expensive, addictive, and toxic medications — but to improve your health and live pain-free, you just need to boost your systemic proteolytic enzymes.

“Arthritis and Joint Pain Breakthrough!”

How This Overlooked “Joint Pain Protein” Is The Real Cause of Your Misery…

…and the Secret to LASTING Relief Without Prescription Drugs 

>>Click here to watch the video<<

See Also:

The powerful health benefits of proteolytic enzymes

Big Pharma says this cure is not ‘economically viable’

Bromelain health benefits that will inspire you to eat pineapple

Filed Under: General Health
Written By:
Jesse Cannone, CFT, CPRS, MFT

Jesse Cannone, CFT, CPRS, MFT

Jesse is the co-founder and visionary CEO of The Healthy Back Institute®, the world-leading source of natural back pain solutions. His mission as a former back pain sufferer is to help others live pain free without surgery and pharmaceuticals.

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55 thoughts on “Fibrin: The Sticky Protein Behind Joint Pain and Inflammation”

  1. Avatar Carol Cannarella says:

    I love this product. Its soooo worth the cost. It not only numbs the pain it helps to heal!

    1. Avatar Chrissie champion says:

      Hi , I’m about to start taking heal and soothe – are you still taking it? If so, are you still getting benefit? Chrissie Champion

  2. Avatar Peter says:

    I started taking Heal-n-Sooth three weeks ago – I started pooping 2 to 3 times a day full formed poops – not sure where all that is coming from but I knew I needed to detox ?

    1. Avatar Perry says:

      I have had debilitating arthritis in hips for 10 years. I can walk or stand only limited amounts. I have been taking the product for four weeks. Ten capsules a day. I can definitely get my left foot-sock on easily. My walking this week has became easier. I started taking stairs instead of elevator. My number of steps increased this week and I wasn’t trying. I still have another day of steps to go before the week is closed. According to the pamphlet that came with the product I’m progressing on schedule. I’m looking forward to more results as well as doing some yard work

      1. Avatar Admin says:

        Hi Perry,
        Thank you so much for taking the time to leave feedback on your progress.We are very happy to hear that you are doing so well!
        Do please contact us if you feel you need any further advice

        Our Very Best Wishes
        Admin(The Healthy Back Institute)

      2. Avatar LARRY says:


        1. Avatar Steve HBI-Staff says:

          Larry, some people do take more for a short period of time called an (activation dose) and then they go or stay with what is called a (maintenance dose).

          There are many factors that people use to consider how much to take like Age, Activity level, location of the condition, the severity of the condition. In general, people start with 3 capsules and add one per day till they feel it working, so you could feel it at 3 and never need to add more. It all depends on you the individual.

  3. Avatar Kent says:

    Peter, how many a day are you taking?

  4. Avatar Cindy solsman says:

    I have chronic migraine headaches. Is there any way fibrin could be involved in them? For one thing I hit the windshield in two car accidends. Also the muscles in my neck and shoulders are always extremely tense. What do you think.

    1. Avatar Kathryn Ellison Lapides says:

      I suffer from CFS, migraines, Lyme disease, costochondritis. The Lyme which is in The autoimmune category of diseases is constantly releasing pro-inflammatory cytokines. After 3 abdominal surgeries, ‘I feel stuck’ inside. Currently have symptoms of bowel obstruction which I am seeing a GI for at Cedars. Could this product help break down scar tissue that is years old?
      Thank you,

      1. Avatar Admin says:

        Hi Kathryn,
        Thank you for your question. Yes it can regardless of how long it has been there, it just takes time…

        Our Best Wishes
        Admin(The Healthy Back Institute)

    2. Avatar Lela says:

      When i had pain from my osteoarthritis 1st stage i was even more desperate when it started hurting at night. That meant no sleeping because i didn’t want to take meds since they ruined my stomach.
      I prayed for healing n help from God. Within days the Holy Spirit said CUT OUT SUGAR. I did and within days pain and stiffness disappeared. I continued and i noticed that my migrain headaches were gone too. I always had allergies to food or inhalants. Every time i went back to eating sweets the pain in my knees n migraine came back.
      Only later i found a video about Fibrin n saw the connection. In 1 year i had lost 11kg – 24lbs n it stays there. Eternally grateful to God.

      1. Avatar stephanie says:

        do you take any prescription medicines. I am not sure if this will interact with my meds

  5. Avatar Steve says:

    Cindy S,

    There are several causes for migraines so I can not tell you specifically why you get them or specifically how to resolve them however, if blood flow regulation has any part of your causes, the use of systemic enzymes could play a role in support of healthy blood flow, and that help everyone…

    Steve HBI-Staff

    1. Avatar Kathryn Nolan says:

      Hi my 15 yr old daughter came down with a inflammatory virus which has attacked her joints she in August. For the last year no meds or steroids help her would this help
      Worried mother

  6. Avatar Alvin says:

    Can this be used to treat Peronies?

  7. Avatar Steve says:

    Alvin, I have no proof that Heal n Soothe can help Peronies, but we can say the enzymes can support the body in regulating scar tissue systemically throughout the body…


  8. Avatar Ocsar Jones says:

    Not a peep about Magnesium’s role in preventing and removing fibrin?

  9. Avatar Steve says:

    Ocsar, Thanks for the feedback, I will have some article written about Magnesium’s role in removing fibrin…

    Steve HBI-Staff

  10. Avatar Tommy Reed says:

    Starred taking Heal and Sooth about 10 days ago. I started with 3 a day first 4 days then increased to 4 a day for the next 4 days. I am back to 3 a day now and I feel so much better. The pain has decreased to almost nothing. Thank God I am off the Advil and Tylenol.

  11. Avatar Juanita G. Manigault says:

    Maybe I overlooked the answer to this question, where is this product at a whole food store or does it have to be ordered.

    1. Avatar Admin says:

      Hi Juanita,

      Thank you for your question. All of our products including the Heal-n-Soothe can be ordered via this page below. Click on any of the products you are interested in to learn more about them and order as you wish.

      Best Wishes, Thank you
      (The Healthy Back Institute)

      1. Avatar Maria Estela Ligmayo says:

        Do you give free samples of Health n Soothe? I like to try it then i will order 1 bottle. Do you have outlet in Calgary AB Canada? My friends and relatives are interested to try it to ease their sciatica pains and back pains.

        1. Avatar Steve HBI Staff says:


          1. No, we do not have an outlet in Calgary or anywhere in Canada

          2. Yes, we can ship Heal n Soothe anywhere in Canada from the USA.

          3. Right now (Oct 2017) we do not give free samples with orders but we do offer discounted offers at time of purchase, when you call 1-800-216-4908



  12. Avatar Ross says:

    Would this product work or be good for a person who has fybromylagia

  13. Avatar Steve says:

    Ross, I have personally sent you a Special Report on Fibromyalgia…

    Please check your inbox



    1. Avatar Deanna says:

      Hello Steve. I’ve suffered from chronic pain (from fibromyalgia, achalasia, arthritis, back fusion, neurology, surgeries, accidents, etc.) for over 20+ years. I’ve been on strong pain medications and muscle relaxers for many years but continue to have awful pain in a daily basis.

      So, I’m very interested in learning more about Heel-N-Soothe. First, would you mind sending me the fibromyalgia information you provided to another person (I believe in November, 2017) and second, is there a trial supply (maybe 7 days) of Heel-N-Soothe available for purchase prior to buying a month, or two or more? (One factor for me is the cost because of being on a limited income.)

      Thank you in advance for your response.

      1. Avatar Admin says:

        Hi Deanna,
        Thank you for your request and questions. Just to let you know that we have sent you personally the Special Report on Fibromyalgia as you requested. Please look out for it on your email.

        If you would ever like to contact us directly you can open a ticket and ask us any questions you would like.

        Thank you, Our Best Wishes
        Admin(The Healthy Back Institute)

  14. Avatar Joanne Ridley says:

    Hi I have severe abdominal and bowel adhesions would soothe n heal help me? I’m sick of popping opioids, I’ve also been in them for years and they don’t work as well as they used too

  15. Avatar Joanne Ridley says:


    I have severe abdominal and bowel adhesions
    Would soothe and heal work for me ?
    So the moment in take big opiopds have been for years and I’m desperate to get off them

    1. Avatar Steve HBI-Staff says:

      Joanne, The bowel adhesions them selfs is not an issue, but we would ask you to consult your physician on the matter of using Enzymes and working your self off opioids…



  16. Avatar Patricia Clark says:

    what are bowel adhesions and why are they not an issue? I have lots of scar tissue and some of it is from Colin reconstruction. Would heal-n-soothe help any scar tissue?

  17. Avatar Steve says:

    Patricia, we would ask you to consult your physician, to see if you have any ulcerations after the reconstruction, please note the intestinal tract needs to be intact and healthy in order for the enzymes to effectively pass through the intestinal lining and make it into circulation…If the intestinal lining is not intact the enzymes could cause and an irritation…

    Thanks for the question

    Steve HBI-Staff

  18. Avatar Claudia says:

    My husband suffers from psoriatic arthritis
    At the moment he is hospitalized fir the third time with an staph infection MSSA…his immune system is very weak…the doctors keep finding abscess to drain the infection.
    I wanted to see once he’s home recovering from this nightmare can your heal n soothe pill help him find some relief for his severe flair ups and out of control immune system?
    He’s been fighting this MSSA infection for about 6th months going back and forth to hospital…

  19. Avatar Ann Barrow says:

    I’ve had fibro myalgia for over 20 years and have tried many pain medications. At present I take 4mgs of Prednisone a day which really helps, but am getting side effects now after being on that for over a year. Is your Heal & Soothe available world wide, and is it very expensive?

    1. Avatar Steve HBI-Staff says:

      Ann, Yes we can ship our Heal n Soothe internationally, however, there are some countries that to put restrictions on it citizens, limiting what you can import for personal use.

      You can learn more about shipping restrictions here:



      1. Avatar jacqueline whitted says:

        Hi Steve ! I have sciatica problems . Some arthritis and Fibromyagia could Heal And Soothe help me

        1. Avatar Steve HBI-Staff says:


          Yes, Heal n Soothe can help your body from a physiological point of view, in that it can support optimal blood flow, the enzymes can help break down and remove any toxins from the area that is irritating the sciatica nerve and it can help support a balanced inflammatory response.


          Steve HBI Staff

  20. Avatar Julie knapp says:

    How do the protiolytic enzymes survive the digestive processes in the stomach and small intestines? And, since they are fairly large molecules, how are they absorbed into the blood, still intact ? How are they “protected”?

    1. Avatar Steve HBI-Staff says:


      There are two things science does not know about enzymes…
      1. They do not know what they look like, as there are no images of an enzyme
      2. They do not know how they are absorbed…
      However, they know that they are as these studies show, it to be so…

  21. Avatar Cynthia says:

    You never mentioned Rheumatoid Arthritis. Will the enzymes help this condition?

    1. Avatar Steven Hefferon says:

      Cynthia, Everyone is different and will respond differently, results are very but there are root level issues that everyone should follow, including addressing and nutritional imbalance, in this case if you are deficient in enzymes there is a good possibility that you could see and feel differently…

      Here is one user or Heal n Soothe that had RA…

      “I have been taking Heal n Sooth and Super Joint Support for an immune deficiency, RA, OA, fibromyalgia and other Neuro disorders for a little over a month and the results are amazing! I no longer have to do my RA injection or my immunoglobulin infusion and I’m healthier and in less pain than I’ve been since I got sick! My iG levels are normal for the 1st time in 11 years. I’m so grateful for these supplements and I’ve found I have to take both for the best benefits. I also have the topical cream for those extra pains and it works wonders. Friends have commented on how great I look and I tell them all about these miracle supplements. Thank you so much!!!!”


      Steve HBI-Staff

  22. Avatar Cheryl A Grandy says:

    What is the ingredient that caused you to state on the label “do not take if suspect you have an ulcer”?

    this product sounds wonderful, and I bought it and was taking it, but I found out I DO have an ulcer

    1. Avatar Steve says:

      Cheryl, The enzymes in Heal n Soothe is the ingredient that caused us to state on the label “do not take if suspect you have an ulcer”…



  23. Avatar Claudia says:

    Would these pills help a person suffering from psoriasis arthritis and had MSSA

  24. Avatar Helena Wall says:

    Hello ! Just taking my first Heal n Soothe plus the Joint supplement today !
    I have had oesteo arthritus for about 17 years. I am a very youthful looking 68 yr old woman, almost 6 ft tall.. I have had both hips and both knees replaced anf a left ankle fusion. Lucky me people still think I LOOK amazing. Here’s hoping I will FEEL amazing soon as well !! My shoulders and rc , elbows, wrists are painful now. Mixed origins for the oa but viral origin is certainly a part. I am also looking into purchasing the “pain zapper”, (which at the right frquency is supposed to kill viruses) as I call it, from this website depending on the cost and availability.. My clever kiniesiologist has one, however I cannot use his often enough. He also has a Physiospec. I have only limited experience with it though..
    Do these enzymes also help with killing n flushing viruses from joints n blood stream , please ? Hope so ! I guess these sups plus the zapper may be ideal for me.
    Thank you so much for reading from me , Helena. Australia.

    1. Avatar Steve HBI Staff says:


      Please let me add a few additional comments to your post…

      1. Please note, the supplements will do wonders for your physiology but remember at almost 6′ there is a physical component to your recovery, please add in some type of physical activity in order to produce balance in your muscles. There is no better way to speed up the process of healing than to combine nutrition and physical activity. (all joint)

      2. The Zapper is awesome, and I have to thank you, just put my unit on the charger:)

      3. The enzymes do help stimulate the immune system, that is why they are not suggested for anyone currently taking an antibiotic…



  25. Avatar Linda Finley says:

    I have been diagnosed with lipodermatosclerosis in my lower legs that is characterized by fibrosis resulting in venous insufficiency. I am thinking about trying Heal-n-Soothe to improve this condition. I am 78 years old and have had RA for 41 years that began with Adult Onset Still’s Disease. I have had both hips and both knees replaced between 2003 and 2008 and they are still in very good condition. This past Aug 1st I was hospitalized 6 days with bleeding diverticula, requiring 2 pints of blood, but no surgery, inflammation or infection. My gastro MD believes that supplements only cause problems, in spite of my having used curcumin to halt 15 years of recurring development of pre-cancerous colon polyps. My greatest concern with Heal-n-Soothe is that it might cause a recurrence of the diverticular bleeding. I have been using Rutin and Aronia to help strengthen blood vessels and capillaries. If Heal-n-Soothe is reasonable, what dose should I start out with? I would also appreciate any other comments you might have.
    I appreciate receiving your e-newsletter about fibrin, as I remembered it when I started to look for natural ways to treat fibrosis.

    1. Avatar Admin says:

      Hi Linda,

      Thank you for your kind words regarding our newsletter. Regarding your question, based on what you have indicated about your intestinal tract, we can not suggest you use any Enzyme supplements.

      Thank you Kindly, Our Best Wishes
      (The Healthy Back Institute)

  26. Avatar Lori Black says:

    I am so angry right now. I began taking Heal-N-Soothe a while back while also seeing a “holistic doctor” for my chronic pain (Psoriatic Arthritis, Hyshimo’s Thyroid, Raynaud’s), . He went through all my supplements and literally threw my bottle in the garbage. He said it was useless and a scam. After several months of seeing this doctor and “stealing” my money, I realized he was the real fraud. Now, I have to start all over with hundreds of dollars lost from this “holistic a**hole.”

  27. Avatar Jenniferann louise Robinson says:

    I ave severe osteoarthiritis in both my feet ,its very painful ,i have had steroid injections in both feet,it gives 4 to 5 weeks relief,can you reccomend anything to help alleviate the pain mrs j robinson

    1. Avatar Steve HBI-Staff says:

      Here are some suggestions to run past your physician…

      1. Custom footwear, in order to support your feet and keep them in a neutral and balanced position so you minimize any irritation caused by weight-bearing.

      2. Sometimes compression stockings are a great way to keep fluids out of the calf and foot.

      3. During those 4-5 months of relief, exercise get those legs stronger more flexible and more stable.


  28. Avatar CORINNE hAIMANN says:


    1. Avatar Admin says:

      Hi Corinne,
      Thank you for your question. We know of no contra-indications, but we have to ask you to consult your physician on the matter. Only they know your complete medical history and only they can answer that question. Thanks HBI-Staff

      (The Healthy Back Institute)

  29. Avatar Nancy says:

    Is this product completely safe? 1. Can someone with a delicate esophagus take papaya products? 2. Can someone at risk of diabetes 2 take these enzymes? (Some enzymes raise the sugar level…?) Please advise. Thank you

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