Should Natural Cleanse™ be taken with food and/or water? TweetShareSharePin0 SharesNatural Cleanse™ should be taken after your last meal and with an 8-ounce glass of water.You may also like to read...Cancer & Wound Healing with EnzymesThe PRICE of Strains & SprainsArthritis Pain? Check Your Teeth…Written By: Updated: May 25,2017