I stopped taking all NSAIDS Immediately (which I have been taking for five years) and started taking the Heal-n-Soothe® Capsules - To my delight about half the burning sensations in the front and sides of my shins disappeared by the second day of use. The awful debilitating Cramps in my Calves and Feet ceased almost altogether - Leaving me now to contend with 'Only' Sciatica in my right buttock and leg - numbness in both my feet and toes and pains in the soles of my feet and heels, like standing on Golf Balls - which in itself is a Great improvement - So I will continue with a further course of the Heal-n-Soothe® Capsules :-) ~ Chris