What Ibuprofen REALLY Does to Your Body

Why Baby Boomers “In the Know” Are
Throwing Out Their Drug Store Pills…

And Switching To A Natural Solution
That’s “Better Than Morphine for Pain…
Yet Safer Than Over-The-Counter Drugs”

If you suffer with arthritis, back pain, or joint pain…

Your first instinct might be to pop an ibuprofen or aspirin to “take the edge off.”

And since they are sold over-the-counter and everyone takes them…

That means NSAIDs like Advil or Tylenol are safe, right?

Far from it.

First, it’s a well-known fact that NSAIDs like can cause serious health issues like gastrointestinal bleeding.

And perhaps you heard about the May 2017 study published in the British Medical Journal…

That shows NSAIDs increase your risk of suffering a heart attack! (In other words, they could kill you — even when taken as directed.)1

And now troubling new research reveals NSAIDs also increase your risk of bone fractures.2

A study published in the Journal of Bone and Mineral Research looked at active-duty soldiers who’d been diagnosed with a stress fracture.

They found soldiers taking an NSAID nearly tripled their risk of developing a stress fracture.3

And the chances of developing a stress fracture during basic training for those taking NSAIDs increased more than 500%!

Now, you might be wondering…

What do the soldiers’ bones have to do with your bones?

Well, think of it like this…

These are young, healthy, physically fit men and women in their late teens and early 20s…

Their bodies are stronger now than at any other point in their lives… but they are getting fractures after taking NSAIDs to manage their chronic pain!

That’s NOT a good sign for the rest of us, who maybe aren’t as physically strong and fit as we once were.

And if you’re over 65…
It could be a matter of life and death

You see, starting at around age 50, studies show your bones become more brittle.

In fact, 1 out of every 2 women and 1 out of every 5 men over the age of 50 will eventually break a bone.

And what’s especially scary, is suffering a fracture when you’re over 65 could kill you!

According to the National Council on Aging, 1 in every 4 Americans over 65 falls each year.

And 1 in every 5 falls results in a traumatic injury, such as a broken bone…

And every 19 minutes, an older adult dies from a fall!

Here’s the kicker… 90% of all NSAID prescriptions go to patients over the age of 65. And 7 in 10 Americans over 65 use NSAIDs every single day.

Now, why on earth would anyone take something that puts you at greater risk of a bone fracture, gastrointestinal bleeding AND a heart attack?

The answer is probably because you’re in pain. I get it. As we get older, we are more likely to suffer aches and pains — and some people live in constant, chronic pain.

It’s really not fair, is it?

Well-meaning doctors keep pushing these pain meds to “help” you, but all you’re really doing is trading one set of problems for another.

If you’re one of those people currently using NSAIDs to manage pain, I understand. I know first-hand what it’s like to live with chronic pain — and why sometimes you may be willing to overlook the potential side effects just to get a little relief.

It’s easy to convince yourself that those scary side effects are something that will happen to someone else … until they happen to you.

Fortunately, there’s a MUCH BETTER option for pain relief…

And I’m going to share it with you today.

It’s safe, non-addictive… and gives you LONG-LASTING relief.

In fact, it’s so powerful…

European doctors say it’s…

Better Than Morphine for Chronic Pain…
…Yet Safer Than Aspirin

In a moment, I’ll you why this SAFE and EFFECTIVE solution has been covered up for more than 70 years…

And how a Columbia University doctor used it to relieve the chronic pain of celebrities like JFK, Marilyn Monroe, Pablo Picasso, and Charlie Chaplin…

But first…

You need to be told the TRUTH about your pain…

No matter how bad your pain is now… or how long you’ve been struggling with it…

You absolutely can decrease — and even eliminate — your chronic pain…

You can get lasting relief WITHOUT drugs and without making your pain WORSE through expensive and often risky surgery…

And you can do it all from the comfort and privacy of your own home.

I know… I did it myself using the SAME discovery I’ll be sharing with you today…

Yes, I was fortunate… I was able to avoid surgery and make a full and complete recovery from my knee injury that kept me in pain for years.

And I’ll tell you how I did it in just a minute…

But honestly, my pain may not have been as serious as yours.

And for that reason, you owe it to yourself to read this special report to the very end, so I can share this fantastic solution for long-term pain with you…

Whether it’s arthritis pain, joint pain, back pain, or ANY other chronic pain that keeps you in “pain prison.”

By the end of this special report, you’re going to walk away with a PROVEN natural solution for your pain…

Because if YOU have chronic pain…

You have every right to be scared.

Not only does your pain make you irritable, exhausted, and angry…it isolates you from the people you love.

Chronic pain pulls you off the playing field and drops you on the SIDELINES like a helpless cripple…

And if you’re reading this today, I know you have your own personal story of feeling sidelined by chronic pain…

How many times have you felt guilty telling people “no” you can’t go out because you’re having a bad pain day?

How many times have you felt powerless because you can’t tie your shoes, open a jar, or even button a shirt without searing pain?

Losing your chance to contribute and lead a productive life can feel like a fate worse than death… trust me, I know… I’ve been there, too!

It’s no wonder so many chronic pain sufferers fall prey to depression and suicide…

And here’s the real kicker: Mainstream Medicine’s so-called “solution” to chronic pain not only doesn’t work, but it may very well kill you!

In fact, it’s destroying lives and families all over the world.

And it’s not just over-the-counter NSAIDs…

Have you ever heard of — or taken — hydrocodone?

Or OxyContin?

Or fentanyl?

These are the synthetic pain pills behind the world’s opioid crisis, the prescription drug disaster you’re hearing about on 60 Minutes… and reading about in every newspaper in the country.

Celebrities like Tom Petty, Prince, and Carrie Fisher were all victims of the opioid crisis. And these pain drugs kill thousands more every MONTH while drug companies reap billions.

It’s not just tragic… it’s sickening.

So let me ask you…

What if you could take a natural alternative that gave you the pain-relieving rush of morphine… without the risk of addiction or death?

You’ll never hear this from your doctor, but such a solution already exists.

Truth is, this natural painkiller has been around for over 70 years… but it’s been routinely IGNORED and SUPPRESSED by the big drug companies for decades.

So what’s the secret to this safe, natural pain reliever?

It’s a combination of unique, painkilling enzymes.

Decades ago, a reclusive MD and Columbia University professor Dr. Max Wolf discovered how a special type of enzyme works to relieve pain.

And he used them extensively in his medical practice.

But in spite of his high-profile patients like JFK, Marilyn Monroe, Pablo Picasso, and Charlie Chaplin, Dr. Wolf’s breakthrough was marginalized by mainstream medicine… Some even say it was blacklisted.

And by the early 1970s, these natural enzymes were killed off by the meteoric rise of Big Pharma’s new pain pills.

These pain pills — a chemical copy of heroin — are the same pain pills behind today’s opioid crisis killing thousands of innocent people every month.

But even if you’re one of the lucky ones who survive this epidemic…

You’re running out of time…

Once you’re over 50 life speeds up… the years start disappearing at a blistering pace…

I bet some days you probably wonder if you’ll EVER have a normal, pain-free day again…

But now you have another choice…

You have a BETTER and SAFER option…

You really do have a reason for NEW hope…

In just a moment you’ll discover how Dr. Wolf’s pain breakthrough gets you off the couch and back to living an active, happy, pain-free life.

There are stacks of clinical, peer-reviewed evidence proving Dr. Wolf’s breakthrough pain solution is the “real McCoy” at freeing you from this endless cycle of agony… without the risk of addiction and death.

In just a moment, you’ll discover:

  • How this pain secret reverses decades of chronic pain…
  • How it restores youthful joints, and everyday mobility…
  • Why it’s safer and more effective than prescription pain pills…
  • And how you can use it without a prescription or even a doctor’s visit…

But first, I want to share my own personal story of struggle with chronic pain. You see, I was in constant pain, too. I was desperate and I didn’t see a way out.

Until I tried Dr. Wolf’s pain-relief protocol for myself…

When I discovered this natural painkiller is ALREADY being used in Europe, I was amazed by the amount of published research available.

Doctors found that when given at the right dose and combination this natural, painkilling protocol:

  • Eliminates aches and pains
  • Reduces swelling and inflammation
  • Kills viruses and bacteria, boosting immune function
  • Improves circulation, decreases high blood pressure and improves heart health
  • Speeds up recovery from traumatic injury
  • Reduces scar formation, and…
  • Prevents serious complications after an injury

I know it gave me relief when I needed it the most…

You see, back when I was 20-years old, I was fresh out of the Navy after a 6-month tour of duty in Europe and the Middle East on the aircraft carrier USS Enterprise.

I was young, ambitious, and ready to take on the world. But after coming home, I severely injured my knee during a 12-mile run.

So just as I’m starting a new career as a fitness trainer, and going to school to become an injury and rehabilitation specialist, I couldn’t even walk… much less workout, or train my clients.
After seeing multiple doctors they STILL couldn’t find anything. So my doctor of “last resort” gave me a cortisone shot, a bottle of 600mg Ibuprofen, and scheduled a surgical procedure for later that month.
Right then and there I decided I was NOT going down that road.

And when I discovered the work of Dr. Max Wolf…

That’s when everything started to click…

You see, Dr. Wolf discovered that our bodies produce a specific type of ENZYME that’s primary job is to kill pain and heal damaged tissue.

Studies suggest these enzymes help your body repair damaged tissue.

But here’s the bad news… Dr. Wolf found your production of these enzymes slows down after around the age of 27… and drops off a cliff after age 50.

But Dr. Wolf discovered a natural way to reintroduce these painkilling enzymes back into your body…

He called it…

Systemic Multi-Enzyme Therapy (SMET).

It’s so effective, you can “switch off” years of joint pain in a matter of weeks (or days even!)…

Systemic multi-enzyme therapy works so well because these enzymes have an analgesic, or pain-relieving, effect like morphine — but without the risk of addiction or death.

And there’s a stack of clinical studies that back this up…

One study looked at people having oral surgery. Each patient had two separate — but comparable — procedures, one on each side of the mouth.

After the first procedure, the patient received these pain-relieving enzymes.

After the second, they received a placebo.

Patients who received the enzymes reported FASTER recovery with LESS pain and swelling.4

In another study, 160 women who’d had a surgical procedure while giving birth were given either enzymes for pain, or a placebo.

After just 4 days, 96% of the women taking the enzymes said their pain was COMPLETELY GONE.5

Another study in the medical journal Arthritis shows a certain enzyme combination may be just as effective as NSAIDs (like Tylenol and Advil) — and could stop the reliance on acetaminophen — in the management of chronic knee osteoarthritis.6

These studies are BIG NEWS if you’re one of millions who can’t leave home without making sure you’ve stashed a bottle of pain pills in your car, purse, or briefcase.

The drug companies won’t tell you this, but a study from the University of Rochester shows NSAIDs decrease your body’s production of antibodies.7

Antibodies are special proteins that help your immune system destroy viruses, bacteria, and other chemicals.

The more antibodies your body has, the easier it is for your body to fight off sickness and disease.

Wiping out your body’s production of antibodies with constant NSAID use could be setting you up for disaster.

Especially when statistics show viruses and infections are a MAJOR killer of people over 65.

Not only are enzymes on par with NSAIDs when it comes to pain-relief…

But Enzymes are proven to BOOST your immune system and help your body eliminate viruses and bacteria from your body.

Another 160 peer-reviewed studies prove systemic multi-enzyme therapy speeds up healing, boosts your immune system, and most importantly:

Reduces inflammation.

Inflammation is a hot topic right now. And for good reason.

When you wipe out inflammation, you wipe out your pain.

While some inflammation — like the redness and swelling around an injury — is a healthy, natural response from your body’s immune system…

A 14-page TIME magazine8 spread revealed chronic inflammation is the root cause of ALL disease — including joint pain that robs millions of Americans of their independence.

Systemic multi-enzyme therapy helps control your body’s inflammatory process. It reduces internal swelling, helps blood cells absorb more nutrients, and improves circulation by breaking down waste and debris.

This ramps up oxygen flow to damaged tissues.

And it means your achy joints and muscles heal MUCH FASTER.

Health experts have yet to find another solution that works as well as reducing inflammation as systemic multi-enzyme therapy.

And doctors worldwide agree the most important thing you can do for pain-relief and avoiding diseases like arthritis, cancer, heart disease, diabetes, multiple sclerosis, and Alzheimer’s… is reduce chronic inflammation.

Chronic inflammation is constant, non-stop inflammation raging throughout your entire body.

It serves no useful purpose.

And in response to inflammation that never goes away, your body produces too much of a “sticky” protein called fibrin.

Have a look at this picture taken with a scanning electron microscope… it shows fibrin as a white, sticky net that TRAPS red blood cells.

And that’s BAD NEWS because red blood cells carry OXYGEN to your cells.

This fibrin web is caused by chronic inflammation… and it’s the barrier that prevents oxygen from getting to your wound.

Now fibrin is a natural part of your immune system, and your body uses fibrin to make scar tissue.

Fibrin is helpful in the right dose.

But when chronic inflammation makes your body produce MORE fibrin than it’s equipped to handle… BAD things happen.

Excess fibrin blocks blood flow. It traps red blood cells. It prevents blood and oxygen from reaching damaged tissues.

And it causes a buildup of scar tissue, which means you can’t bend and flex your joints.

The result?

Your body cannot heal itself…

You suffer from chronic joint pain, back pain, and arthritis…

Your pain and injuries NEVER go away.

While this is news to most Americans, German scientists have known about the “fibrin-inflammation connection” for decades.

That’s why European doctors use Dr. Wolf’s systemic multi-enzyme therapy.

Dr. Wolf’s enzyme therapy is standard treatment for pain in almost every hospital in Germany.

The German Olympic Team uses enzymes too…

Trainers for the German and Austrian Olympic teams caught on to the painkilling power of enzymes back in 1984.

German physicians needed a solution to help athletes recover between competitions. Opiate painkillers made players feel “doped up” and sluggish.

So German scientists tested systemic multi-enzyme therapy on a random group of 100 hockey players.

The result?

Players who took systemic multi-enzymes between games recovered faster, had less swelling, and performed better than players who didn’t take the enzymes.

German doctors and players were so impressed at how well the enzymes stopped pain, ALL German athletes now receive systemic multi-enzyme therapy.

They believe so strongly in enzymes therapy, Germany and Austria ordered more than ONE MILLION enzyme capsules for their athletes for the 1998 Winter Olympics.8

And today, the company that manufactures those enzyme capsules is an official supplier and sponsor of the German Olympic team.

You see, German doctors know that over time, the body repairs even the most painful joint or muscle… as long as you clear out the excess fibrin.

And here’s what I’d like you to remember:

You can easily give your body a new supply of healing enzymes that clear out excess fibrin and RELIEVE PAIN.

And you don’t need a prescription from a German doctor.

Or ANY doctor…

My research team and I formulated a systemic multi-enzyme solution based on Dr. Wolf’s research we call, Heal-n-Soothe®.

And today, I’d like to send you a FREE bottle. Just cover a small shipping charge.

You see, I KNOW the systemic enzymes in Heal-n-Soothe are the real deal for eliminating pain…

…and so do the tens of thousands of people around the world who rely on Heal-n-Soothe to help them live pain free.

I know if you FEEL it for yourself the “lightbulb” will go off and suddenly you’ll be like, “OMG… I get it!”

Now for the first time, you can get your hands on a safe and effective pain reliever… without prescription drugs and without the worry of addiction or death.

Our proven formula delivers the most powerful systemic enzymes and pain-fighting superfoods.

Heal-n-Soothe® is a combination of multiple systemic enzymes like Protease AM, Protease 6.0, Alkaline Protease… PLUS an extract of ginger and the inflammation-fighting enzymes from pineapple and papaya called Bromelain and Papain.

All of these ingredients are proven to cut through excess fibrin, reduce inflammation, and promote pain relief.

As you’ll see below, Heal-n-Soothe® has changed the lives of tens of thousands of everyday folks just like yourself…

And today, you can get a FREE bottle and feel first hand how systemic multi-enzyme therapy melts away pain and discomfort you may have been struggling with for years… or even decades.

Just click the button below to reserve your free bottle now.

When you accept my invitation for your FREE bottle of Heal-n-Soothe® today you will very likely be the next pain sufferer who FINALLY gets lasting relief…

It happened for Greg Moormann… and it could happen for you, too!

Greg calls Heal-n-Soothe® “God in a bottle…”

Here’s his amazing story…

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Disclaimer: Results not typical. Your specific results may vary.

I love hearing stories like this… and we have hundreds of them on file.

From people just like you… finally getting relief from their chronic pain without having to rely on dangerous prescription drugs.

So why am I going to send you a FREE bottle, instead of selling it at the regular price of $59.95?

Because what we have works.

Heal-n-Soothe® works.

But I don’t expect you to take my word for it.

In a world where so many people are just out to make a buck, we are taking a stand.

We want Heal-n-Soothe® to be a valuable part of your life. So if it doesn’t work for you, that shouldn’t be YOUR problem… it should be ours!

And that’s why we’re going to shoulder 100% of the risk for YOU to give Heal-n-Soothe® a try. If it works for you, we trust you’ll stick with us and become a valued customer.

If it doesn’t, you risk nothing.

Frankly, I’m not sure how long we’ll be able to keep this available. I’m doing my best here to lead with my heart and extend this offer to as many people as possible.

This is my way of getting to you FIRST. Before this dangerous opioid crisis claims YOU as its next victim.

But I can’t promise this will last forever. This free bottle offer doesn’t even cover our costs… so I’d highly recommend you claim your FREE bottle before we pull the plug on this special giveaway.

On our main website, Heal-n-Soothe® sells for $59.95 per bottle. And our customers are happy to pay that for one reason and one reason only:

Heal-n-Soothe® Relieves Pain…
And It Can Relieve Yours Too!

And now with this very special offer, you get to give it a test drive free!

We don’t want to “sell you” on Heal-n-Soothe®. Instead, we want to earn your business by letting you put it to the test, in your own life… by relieving your own pain!

To be fair, here’s how this works.

My offer to give you a FREE bottle of Heal-n-Soothe® is valid TODAY ONLY.

After that, it’s gone… although you’re welcome to go to our main website and purchase a bottle for the regular price.

That way everyone gets a fair shot.

To reserve your bottle, simply click the button below.

And don’t be fooled by cheap imitations and companies that hide the Exact Ingredients and concentrations of critical pain-killing enzymes…

As you can see, we’re not hiding anything…

Here’s the EXACT list of ingredients AND concentrations…

On their own, each of these ingredients have been proven through both clinical studies and thousands of years of use to be safe and effective.

But together, they work synergistically to quickly reduce inflammation and relieve chronic pain.

Heal-n-Soothe® not only has the most powerful combination of pain-fighting superfoods like ginger, papaya, and pineapple — the top 3 inflammation-fighting superfoods available today…

Heal-n-Soothe® ALSO has the strongest and highest potency of any proteolytic enzyme formulation available! These are the VERY SAME enzymes Dr. Wolf used to relieve his patients of even the most aggressive arthritis and joint pain.

And, unlike most supplement manufacturers who call their formula a “proprietary blend” and don’t say how much of each nutrient is included… we show you EXACTLY how much of each ingredient is in the product.

You will NOT find a more effective natural pain reliever online… or at your local drug store.

We even had a customer call in recently to say he asked his local pharmacist if they had any systemic enzymes and they didn’t even know what he was talking about… scary!

Now, I’ve already told you about Greg Moorman, and how Heal-n-Soothe® relieved his chronic back and sciatica pain… he got relief so fast it was literally overnight.

But that’s not enough.

I want to show you more proof… including an endorsement from an MD who uses Heal-n-Soothe®… and more people from around the world who finally found lasting relief from chronic pain without harmful side effects!

“This is one of the best-formulated products I’ve seen… I give it my strongest recommendation”
-Dr. Robert Thompson, MD

Disclaimer: Results not typical. Your specific results may vary.

“I love Heal-n-Soothe… I’m able to walk around and do the work I need to do”
-Kate Method

Disclaimer: Results not typical. Your specific results may vary.

“The KEY that made me well again”
– Alex Mitchell

Disclaimer: Results not typical. Your specific results may vary.

Systemic Enzymes Have Been PROVEN To Work By
Some Of The Top Research Centers In The World!

A study by the Institute of Cancer Research in Vienna found that “a combination of proteolytic enzymes and herbs were effective in treating rheumatoid arthritis and reducing TGF-b, which is known to be present in the blood when there is cancer.”9

 In a study by Dr. Nicholas Gonzales, published in the medical journal, Nutrition and Cancer, Dr. Gonzales compared systemic multi-enzyme therapy against a new cancer drug, Gemcitabine. He found that 5 out of 11 patients treated with systemic multi-enzyme therapy lived two years or longer and not a single patient of the 129 treated with the drug lived more than 19 months!10

A study published in the Journal of Medicine and Science in Sports and Exercise found that, “systemic enzymes have therapeutic effects in the treatment of inflammation and soft tissue injuries.” 11

Keep in mind that drug companies can’t patent natural substances like vitamins, minerals and, yes, proteolytic enzymes.

And no patent means no blockbuster drugs that make tens of billions of dollars in profit…
Once again… when it comes to drug companies… they care about the MONEY… not you.

So Far, You’ve Discovered 3 Scientifically-Proven Facts…

FACT #1: There’s likely an overproduction of fibrin occurring in your body right now. And that keeps you in pain by blocking oxygen delivery.

FACT #2: A unique formulation of pain-fighting enzymes — the very same ones Dr. Wolf used to relieve pain in his own patients — are proven to reduce inflammation and relieve pain. With no dangerous side effects.

FACT #3: Unfortunately, your body’s production of these enzymes decreases dramatically around the age of 27… and nearly disappears by age 50.

Now the decision is completely yours…

Do you want to take the risk of dying 5… 10… 15 years early? Or living a lonely and unfulfilling life riddled with pain?

Do you want to continue wasting your money on expensive and dangerous prescription pain meds that are literally eating away at your organs like a cancerous Pac Man?

Or maybe you are ready to try something NEW… something 100% safe… something all-natural which HEALS your body as it:

  • Soothes away your chronic pain…
  • Enables you to enjoy a round of golf or your favorite activity without pain…
  • Restores the strength in your weakened hands and joints…
  • Helps you to stay active with your friends and family…
  • Allows you to be independent once again and live your life without being a burden on ANYONE…

If living life on your own terms sounds like a distant dream, NOW is the time to get back to living the life you deserve.

Look, I know you’re skeptical. You should be. Look at all the big drug companies who are lying to you each and every day trying to convince you that their dangerous (and sometimes deadly!) drugs are the only answer.

There’s no better way for you to find out if Heal-n-Soothe® will work for you, than having you try it. And that’s why I’d like to send you a FULL bottle for FREE. Just cover shipping.

No matter what your pain level and frequency are right now… Click the button below to see for yourself just how well Heal-n-Soothe® will work for you.

Just in case you need a little more reassurance…

Here are 5 Great Reasons To Test-Drive Heal-n-Soothe® Today…

It HEALS and RELIEVES chronic pain instead of just covering it up —Unlike traditional pain medications which simply cover up your pain like a Band-Aid… Heal-n-Soothe® actually HEALS the underlying condition causing your chronic pain. That means you’ll feel quick pain relief in the short-term… and permanent healing in the long-term!

No Dangerous Side Effects — Unlike prescription pain pills and over-the-counter options (NSAIDS)… when you order Heal-n-Soothe® today you’ll never again have to worry about side effects such as internal bleeding, risk of liver failure or even dying! Heal-n-Soothe® is made with 100% natural ingredients and is as safe to take as your daily multivitamin. In fact… we recommend you take Heal-n-Soothe® WITH your multivitamin!

NO RISK! We’ve Put ALL The Risk On OUR Shoulders— Listen, I know you’re in pain and you want to get rid of that nasty chronic pain. Heal-n-Soothe® can help relieve ANY type of pain, but I’m sure you’re still skeptical. That’s why I’m sending you a full-size, 90-count bottle, a $59 value, for FREE… That’s right, you NEVER pay for this bottle… Just cover a small shipping fee, and we’ll send a free bottle right to your front door.

Feel ALIVE Again! — Journey back to the days of your childhood when aches and pains were only a rarity and you could do what you wanted, when you wanted without worrying about aches and pains getting in your way.

Heal-n-Soothe® actually RESTORES the healing and pain-fighting enzymes you had in abundance when you were younger.

That means a more youthful life with MUCH LESS PAIN pain becomes a reality again as our unique formula fixes the problem at its source instead of just covering it up for a while…

Heal-n-Soothe® is a REAL and PROVEN natural painkiller.

Click the Button Below to Reserve Your Free Bottle of Heal-n-Soothe® Today

And thank you for reading!


  1. https://www.bmj.com/content/357/bmj.j1909
  2. Hughes, J. M., McKinnon, C. J., Taylor, K. M., Kardouni, J. R., Bulathsinhala, L. , Guerriere, K. I., Popp, K. L., Bouxsein, M. L., Proctor, S. P. and Matheny, R. W. (2018),”Nonsteroidal Anti‐Inflammatory Drug Prescriptions Are Associated With Increased Stress Fracture Diagnosis in the US Army Population.” J Bone Miner Res. doi:10.1002/jbmr.3616
  3. Marquez-Lara A1, Hutchinson ID, Nuñez F Jr, Smith TL, Miller AN.“Nonsteroidal Anti-Inflammatory Drugs and Bone-Healing: A Systematic Review of Research Quality.” JBJS Rev. 2016 Mar 15;4(3)
  4. T.H.Al-Khateeb, Y.Nusair.  Effect of the proteolytic enzyme serrapeptase on swelling, pain and trismus after surgical extraction of mandibular third molars. International Journal of Oral and Maxillofacial Surgery, Volume 37, Issue 3, March 2008, Pages 264-268
  5. Magnes GD. Proteolytic enzymes in oral surgery. J Am Dent Assoc. 1966 Jun;72(6):1420-5. PubMed PMID: 5326499
  6. The Safety and Efficacy of an Enzyme Combination in Managing Knee Osteoarthritis Pain in Adults: A Randomized, Double-Blind, Placebo-Controlled Trial
  7. Simona Bancos, Matthew P. Bernard, David J. Topham, and Richard P. Phipps. Ibuprofen and other widely used non-steroidal anti-inflammatory drugs inhibit antibody production in human cells. Cell Immunol. 2009; 258(1): 18–28.
  8. Christine Gorman, Alice Park and Kristina Dell. Health: The Fires Within. Time Magazine. Monday, Feb. 23, 2004
  9. John Beard, Herxheimer, Dr. Inderst, Kleine, Dr. Kunz, Jaeger, Prof. Seifert, Hector E. Solorzano del Rio, M.D., D.Sc, Ph.D, Prof. Wolf, Dr. Wrba.  Systemic Enzyme Therapy. 1994.
  10. Desser, Lucia, et al. “Oral therapy with proteolytic enzymes decreases excessive TGF-β levels in human blood.” Cancer chemotherapy and pharmacology 47.1 (2001): S10-S15.
  11. Gonzalez NJ, Isaacs LL.  Evaluation of pancreatic proteolytic enzyme treatment of adenocarcinoma of the pancreas, with nutrition and detoxification support. Nutr Cancer. 1999;33(2):117-24.
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